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ADVANCES IN THE PATHOPHYSIOLOGY AND MANAGEMENT OF CANCER PAIN: A SCOPING REVIEW Y. Tran Van1, A. Paladini2, V.P. Pham1, A.A. Al Alwany3, G. Farì4, A. Caruso5, M. Mercieri6, M.L.G. Leoni7, J.V. Pergolizzi8, A.D. Kaye9, F. Breve10, A. Corriero11, C. Gharibo12, G. Varrassi13 | 1Department of Biomedical Engineering, International University, Vietnam National University, Ho Chi Minh City, Vietnam; 2Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; 3College of Medicine, University of Baghdad, Iraq; 4Department of Experimental Medicine (Di.Me.S.), University of Salento, Lecce, Italy; 6Department of Surgery, ASST Lodi, Lodi, Italy; 7Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Italy; 8NEMA Research Inc., Naples, FL, USA; 9Department of Anesthesiology, LSU Health, Shreveport, LA, USA; 10School of Pharmacy, Temple University, Philadelphia, PA, USA; 11Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy; 12Department of Anesthesiology, NYU Grossman School of Medicine, New York, NY, USA; 13Fondazione Paolo Procacci, Rome, Italy
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MICROBIOTA–IMMUNE–BRAIN MECHANISMS IN CHRONIC PAIN: A STRUCTURED NARRATIVE SYNTHESIS OF TRANSLATIONAL AND CLINICAL EVIDENCE Y. Tran Van1, P.P. Van1, C.B.N. Uyen2, A. Caruso3, G. Farì4, M.L.G. Leoni5, G. Varrassi6 | 1Department of Biomedical Engineering, International University, Vietnam National University, Ho Chi Minh City, Vietnam; 2Department of Anesthesiology, Vinmec Central Park Hospital, Ho Chi Minh city, Vietnam; 3Department of Surgery, ASST Lodi, Lodi, Italy; 4Department of Experimental Medicine (Di.Me.S.), University of Salento, Lecce, Italy; 5Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Italy; 6Fondazione Paolo Procacci, Rome, Italy
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MULTIMODAL ELECTROPHYSIOLOGIC AND CEREBRAL PERFUSION ASSESSMENT OF LOSS OF CONSCIOUSNESS IN CALVES DURING SLAUGHTER: TRANSLATIONAL IMPLICATIONS FOR PAIN CONSCIOUSNESS MONITORING V.P. Pham1, V.Y. Tran2, A.A. Al Alwany3, G. Farì4, D. Myrcik5, N. Cimini6, M.L.G. Leoni7, G. Varrassi8 | 1Department of Biomedical Engineering, International University, Vietnam National University, Ho Chi Minh city, Vietnam; 2Department of Biomedical Engineering, International University, Vietnam National University, Ho Chi Minh City, Vietnam; 3College of Medicine, University of Baghdad, Iraq; 4Department of Experimental Medicine (Di.Me.S.), University of Salento, Lecce, Italy; 5Department of Internal Diseases Propaedeutics and Emergency Medicine, Medical University of Silesia, Bytom, Poland; 6Department of MESVA, University of L’Aquila, Italy; 7Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Italy; 8Fondazione Paolo Procacci, Rome, Italy
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FROM DYSBIOSIS TO CENTRAL SENSITIZATION: A SCOPING REVIEW OF GUT-BRAIN SIGNALING IN FIBROMYALGIA V.P. Pham1, V.Y. Tran1, F. Breve2, M.L.G. Leoni, D. Myrcik4, G. Varrassi5|6 | 1Department of Anesthesiology, Tam Anh General Hospital, Ho Chi Minh city, Vietnam; 2Mid Atlantic PharmaTech Consultants LLC; Temple University School of Pharmacy, Philadelphia, PA , USA; 3Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Italy; 4Department of Internal Diseases Propaedeutics and Emergency Medicine, Medical University of Silesia, Bytom, Poland; 5Department of Research, Fondazione Paolo Procacci, Rome, Italy; 6College of Medicine, University of Baghdad, Iraq
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DEEP BRAIN STIMULATION FOR REFRACTORY CHRONIC PAIN: CLINICAL TARGETS, INDICATIONS, AND EMERGING STRATEGIES L. Al-Husinat1, S. Azzam1, S. Al Sharie2, A.A. Alomari3, A. Baydoun4, H.B. Yaseen5, G. Varrassi6 | 1Department of General Surgery and Anesthesia, Faculty of Medicine, Yarmouk University, Irbid, Jordan; 2Laboratory of Science and Translation in Critical Illness, Vanderbilt University Medical Center, Nashville, TN, USA; 3Section of Neurosurgery, Department of Special Surgery, Faculty of Medicine, Mutah University, Alkarak, Jordan; 4Unit of Anesthesia, Intensive Care and Pain Therapy, Sant’Andrea University Hospital, Rome, Italy; 5Department of Anesthesia and Intensive care unit, Ministry of Health Educational Hospitals, Amman, Jordan; 6Fondazione Paolo Procacci, Rome, Italy
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THORACOLUMBAR JUNCTION SYNDROME AS AN UNDERRECOGNIZED SOURCE OF PELVIC AND HIP PAIN: DIAGNOSTIC AND THERAPEUTIC IMPLICATIONS S.C. Longo1, F. Quarta2, S. Lanza1, L. De Palma3, G. Frasca3, R. Lopes4, G. Farì5 | 1Rehabilitation Unit, M. Paternò Arezzo Hospital, Ragusa, Italy; 2Department of Biological and Environmental Science and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy; 3Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari "Aldo Moro", Bari, Italy; 4Department of Biomedical and Biotechonological Sciences, University of Catania, Italy; 5Department of Experimental Medicine (Di.Me.S.), University of Salento, Lecce, Italy
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PAIN AS A NEUROCARDIAC STRESSOR: REFRAMING PAIN BEYOND NOCICEPTION C. Angeletti1, G. Di Giuseppe1, I. Olivieri1, G. Varrassi2 | 1Department of Anaesthesia, Intensive Care and Pain Medicine, Mazzini Hospital, Teramo, Italy; 2Fondazione Paolo Procacci, Rome, Italy
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FROM GENES TO SYMPTOMS: SENSORY PROFILING IN CHRONIC PAIN PATIENTS WITH TRPA1 AND SCN9A MUTATIONS M. Marchi1, A. Telesca1, E. Salvi1, M. Andelic1, A. Strippoli1, I. D'Amato1, R. Lombardi1, D. Cartelli1, D. Cazzato2, M. De Tommaso3, G. Lauria1,4, G. Devigili1 | 1Department of Clinical Neuroscience, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano; 2SC Neurophysiopathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano; 3DiBrain Department, Aldo Moro University, Bari; 4Department of Medical Biotechnology and Translational Medicine, University of Milano
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