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Advancements in Health Research

eISSN 3035-1103

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Editors-in-Chief: Pierangelo Geppetti, Giustino Varrassi, Italy

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  • Systematic review of endoscopic botulinum toxin injections for refractory gastroparesis

    Chelsi J. Flanagan, Ross Dies, Connor J. Plaisance, Giustino Varrassi, Matthew J. Sharpe, Christopher L. Robinson, Shahab Ahmadzadeh, Adam M. Kaye, Sahar Shekoohi, Alan D. Kaye
    2025-01-22
    https://doi.org/10.4081/ahr.2025.20
    1315
    Downloads: 653
  • PULSED RADIOFREQUENCY ADJACENT TO CERVICAL DORSAL ROOT GANGLION FOR REFRACTORY PHANTOM LIMB PAIN: A SINGLE ARM INTERVENTIONAL STUDY R.S. Sharma1, A. Kumar2 | 1Department of Anaesthesiology, Pain Medicine & Critical Care, All India Institute of Medical Sciences, Gorakhpur, India; 2Department of Anaesthesia, All India Institute of Medical Sciences, Rishikesh, India

    Fondazione Paolo Procacci
    2026-05-06
    https://doi.org/10.4081/ahr.2026.197
    97
  • PERCUTANEOUS RADIOFREQUENCY THERMORHIZOTOMY EFFECTIVENESS IN REFRACTORY TRIGEMINAL NEURALGIA M. Storari1, D. Viscuso2, S. Mameli3 | 1Libero professionista in Milano, Cagliari, Vicenza, Italy; 2Istituto Stomatologico Italiano, Milano e Università di Cagliari, Italy; 3Ospedale Oncologico Businco, Cagliari, Italy

    2026-09-21
    https://doi.org/10.4081/ahr.2026.289
    5
  • SIGNIFICANT PAIN RELIEF AND QUALITY OF LIFE IMPROVEMENT IN REFRACTORY CHRONIC MIGRAINE PATIENT TREATED WITH HIGH-FREQUENCY SPINAL CORD STIMULATION F. Cassini, L. Ventura, A. Berardi | University Hospital "SS. Antonio e Biagio e Cesare Arrigo", Alessandria

    2025-09-22
    https://doi.org/10.4081/ahr.2025.53
    235
  • DEEP BRAIN STIMULATION FOR REFRACTORY CHRONIC PAIN: CLINICAL TARGETS, INDICATIONS, AND EMERGING STRATEGIES L. Al-Husinat1, S. Azzam1, S. Al Sharie2, A.A. Alomari3, A. Baydoun4, H.B. Yaseen5, G. Varrassi6 | 1Department of General Surgery and Anesthesia, Faculty of Medicine, Yarmouk University, Irbid, Jordan; 2Laboratory of Science and Translation in Critical Illness, Vanderbilt University Medical Center, Nashville, TN, USA; 3Section of Neurosurgery, Department of Special Surgery, Faculty of Medicine, Mutah University, Alkarak, Jordan; 4Unit of Anesthesia, Intensive Care and Pain Therapy, Sant’Andrea University Hospital, Rome, Italy; 5Department of Anesthesia and Intensive care unit, Ministry of Health Educational Hospitals, Amman, Jordan; 6Fondazione Paolo Procacci, Rome, Italy

    Fondazione Paolo Procacci
    2026-05-06
    https://doi.org/10.4081/ahr.2026.147
    190
  • IMPROVEMENT OF NEUROPATHIC PAIN AND FUNCTIONAL AUTONOMY IN ADVANCED MULTIPLE SCLEROSIS THROUGH EQUISTASI® TREATMENT: A SIX-MONTH CASE REPORT M. Alfieri1, V. Donatiello1, D. Casale2, F. Mattozzi1, A. Cangiano1, V. Moschella1, P. Buonavolontà1 | 1UOSD Terapia del Dolore AORN "A. Cardarelli", Napoli, Italy; 2UOC Anestesia e Terapia Intensiva PO "Santa Maria della Pietà", Nola, Italy

    2026-09-21
    https://doi.org/10.4081/ahr.2026.228
    29
  • INTRATHECAL MORPHINE THERAPY FOR CHRONIC BENIGN NEUROPATHIC PAIN: A CASE REPORT V. Donatiello1, M. Alfieri2, A. Scalvenzi1, F. Mattozzi2, A. Cangiano2, A.R. Tonci2, P. Buonavolontà2 | 1Dept. of Elective Anesthesiological Activities ", "AORN A. Cardarelli" Hospital Napoli; 2Pain Unit "AORN A. Cardarelli" Hospital, Napoli

    2025-09-22
    https://doi.org/10.4081/ahr.2025.62
    166
  • AURICULAR PERCUTANEOUS NEUROMODULATION (AURIMOD®) FOR REFRACTORY MIGRAINE WITH MEDICATION OVERUSE: A RAPID-RESPONSE CASE REPORT G. Pilerci1, T. Giuliani2, E. Cammarota3 | 1Asl Salerno, Pain Unit Vallo della Lucania, Italy; 2Asl Salerno, Pain Unit,Vallo della Lucania, Italy; 3Asl Salerno,Pain Unit,Vallo della Lucania, Italy

    2026-09-21
    https://doi.org/10.4081/ahr.2026.275
    15
  • MULTIDISCIPLINARY MANAGEMENT OF REFRACTORY FAILED BACK SURGERY SYNDROME: A COMPLEX CASE REPORT WITH MULTIMODAL INTERVENTIONS AND LITERATURE REVIEW D. Gemma1, G. Pulito2 | 1"Cardinale G. Panico" Hospital, Tricase (Lecce); 2"V. Fazzi" Hospital, Lecce

    2025-09-22
    https://doi.org/10.4081/ahr.2025.75
    144
  • SEVERE PAIN AND NEUROLOGICAL SYMPTOMS AS AN INITIAL MANIFESTATION OF PARANEOPLASTIC SYNDROME: A CASE REPORT A. Górecka1, D. Myrcik2, U. Michalik-Marcinkowska3, G. Varrassi4, K. Walkiewicz2, M. Muc-Wierzgoń2, M.S. Świtała5 | 1Department of Health Risk Management, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, Bytom, Poland; 2Department of Propaedeutics of Internal Diseases and Emergency Medicine, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, Bytom, Poland; 3Department of Family Medicine and Public Health, Faculty of Medicine, University of Opole, Poland; 4Fondazione Paolo Procacci, Rome, Italy; 5Department of Health Economics and Health Management, Medical University of Silesia in Katowice, Bytom, Poland

    Fondazione Paolo Procacci
    2026-05-06
    https://doi.org/10.4081/ahr.2026.165
    106
  • NOTALGIA PARESTHETICA: CASE REPORT ON THERAPEUTIC MANAGEMENT WITH ULTRASOUND-GUIDED OZONE MESOTHERAPY S. Sorrenti1, M. Ciuffreda1, E. Pisello1, C. Pellegrino2, A. Monacelli2, G. Cucè4, C. Piangatelli1, D. Galante4 | 1Department of Anesthesiology, Intensive Care and Pain Management, AST Ancona, Fabriano (AN), Italy; 2Department of Anesthesiology, Intensive Care and Pain Management, Marche Polytechnic University, Ancona, Italy; 3Department of Public Health, University of Messina, Italy; 4Department of Anesthesiology, Intensive Care and Pain Management, ASL Foggia, Cerignola (FG), Italy

    Fondazione Paolo Procacci
    2026-05-06
    https://doi.org/10.4081/ahr.2026.198
    124
  • DERMATOME-ORIENTED PENS IN LONG-STANDING THORACIC POSTHERPETIC NEURALGIA: A CASE REPORT G. Di Giuseppe1, I. Olivieri1, C. Angeletti2 | 1Dip.to Anestesia, Terapia intensiva e Terapia del dolore, Ospedale Mazzini, Teramo, Italy; 2L'Aquila, Italy

    2026-09-21
    https://doi.org/10.4081/ahr.2026.241
    9
  • ULTRASOUND-GUIDED CRYONEUROLYSIS: A NOVEL APPROACH TO PAIN MANAGEMENT IN RHEUMATOID ANKLE AND FOOT ARTHRITIS A. Allam1, M. Hassanien2, A.O.M. Abdallah3, K.H.S. Lam4|5|6, T.K. Ng7|8|9|10, T. Ergönenç11, F. Occhigrossi12 | 1Department of Physical Medicine, Rheumatology and Rehabilitation, Faculty of Medicine, Tanta University, Tanta, Egypt; 2Department of Rheumatology and Rehabilitation, Faculty of Medicine, Assuit University, Assuit, Egypt; 3Department of Anesthesia and Intensive Care, Faculty of Medicine, New Valley University, New Valley, Egypt; 4Department of Family Medicine, Faculty of Medicine, the Chinese University of Hong Kong, Shatin, Hong Kong; 5Department of Family Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong; 6Department of Clinical Research, The International Association of Musculoskeletal Medicine, Kowloon Bay, Kowloon, Hong Kong, China; 7Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Hong Kong, China; 8Department of Anaesthesia, Boxhill Hospital, Melbourne, Australia; 9Frankston Pain Management, Melbourne, Australia; 10Department of Anaesthesia and Operating Theatre Services, Tuen Mun Hospital, Tuen Mun, Hong Kong, China; 11Anesthesia and Reanimation, Pain and Palliative Care, Akayazi Hospital, Sakarya, Turkey; 12Pain Therapy Unit, San Giovanni-Addolorata Hospital, Rome, Italy

    Fondazione Paolo Procacci
    2026-05-06
    https://doi.org/10.4081/ahr.2026.148
    222
  • REAL-WORLD TITRATION PATHWAYS AND THERAPEUTIC INTEGRATION OF MEDICAL CANNABIS IN FIBROMYALGIA: INTERIM ANALYSIS OF A REFRACTORY CLINICAL COHORT I. Olivieri, G. Di Giuseppe, R. Berrettoni, C. Angeletti | Department of Anaesthesia, Intensive Care and Pain Medicine, Mazzini Hospital, Teramo, Italy

    Fondazione Paolo Procacci
    2026-05-06
    https://doi.org/10.4081/ahr.2026.181
    103
  • VAGAL NEUROMODULATION FOR DRUG-RESISTANT TRIGEMINAL NEURALGIA: A CASE SERIES C. Tuccillo1, A.M. Salzano2, M.T. Di Dato2, A. Diana1, C. Morrone1, M.B. Passavanti3, C. Pace3, E. Saracco2, M.V. Adriani2, P. Mango2, D. Tammaro2, A. Papa2 | 1Residency Program in Anesthesiology, Resuscitation, Intensive and Pain Therapy University of Campania "Luigi Vanvitelli", Napoli, Italy; 2Pain Department, A.O. Dei Colli - V. Monaldi Hospital, Napoli, Italy; 3Department of Women, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Napoli, Italy

    2026-09-21
    https://doi.org/10.4081/ahr.2026.291
    35
  • HF-SCS (10 KHZ) FOR THE MANAGEMENT OF NEUROPATHIC PAIN AND AUTONOMIC DYSFUNCTION SECONDARY TO IATROGENIC CONUS MEDULLARIS INJURY: A CASE REPORT S. Scolaro1, S.M. Caliò2, S. Caramma3 | 1UOS Terapia del Dolore ASP 5 P.O. "Barone Romeo", Patti (ME), Italy; 2UOC Anestesia e Rianimazione ASP 5 P.O. "Barone Romeo", Patti (ME), Italy; 3UOSD Terapia del Dolore AOU Policlinico “G. Rodolico - San Marco”, Catania, Italy

    2026-09-21
    https://doi.org/10.4081/ahr.2026.281
    22
  • THE COMBINATION OF ZICONOTIDE TO INTRATHECAL BACLOFEN EFFECTIVELY AND SAFELY CONTROL NEUROPATHIC PAIN IN MULTIPLE SCLEROSIS: A CASE REPORT WITH A 4-YEAR FOLLOW UP F. Gloria, M. Giglio, A. Corriero, A. Preziosa, F. Galdini, A. Pilolla, S. Grasso, F. Puntillo | Department of Interdisciplinary Medicine; ICU and Pain Therapy Section, University of Bari “Aldo Moro”

    2025-09-22
    https://doi.org/10.4081/ahr.2025.76
    234
  • IMPLEMENTATION OF A HUB PROTOCOL FOR REDUCING COMPLICATIONS IN SPINAL CORD AND DORSAL ROOT GANGLION STIMULATION: REAL-WORLD EXPERIENCE FROM THE EASTERN SICILY PAIN MANAGEMENT HUB CENTER S. Zappalà1, S. Stimolo2, M. Maria3, S. Brundo3, S. Caramma3 | 1Università di padova, Padova, Italy; 2Università di Padova, Italy; 3Policlinico G. Rodolico- San Marco, Catania, Italy

    2026-09-21
    https://doi.org/10.4081/ahr.2026.293
    9
  • SPINAL CORD STIMULATION AND QUALITY OF LIFE: A RETROSPECTIVE STUDY A. Merlini1, C. Bertone1, D. Boarato2, E. Biordi2, G. Sindaco1, M. La Grua1, M. Mazzullo1, L. Ceciliato1, W. Rossi1, G. Pari1 | 1Pain Unit, Santa Maria Maddalena Hospital, Occhiobello (RO); 2Advanced Algology Research

    2025-09-22
    https://doi.org/10.4081/ahr.2025.85
    147
  • MESOTHERAPY COMBINED WITH REGENERATIVE MEDICINE. A NEW APPROACH FOR NOCICEPTIVE PAIN TREATMENT IN PATIENTS WITH OSTEOARTHROSIS A. Bertolino1, A. Maxia2, B. Pani2, M. Ollosu2, S. Sardo2 | 1Anesthesia, Intensive Care and Pain Therapy Unit, AOU Cagliari; 2Department of Medical Sciences and Public Health, University of Cagliari

    2025-09-22
    https://doi.org/10.4081/ahr.2025.44
    208
  • CAN SCRAMBLER THERAPY BE USED TO TREAT REFRACTORY TRIGEMINAL NEURALGIA? G. Pasian1, M.L. Lissandron1, L. Gumiero2, P. Nosella1 | 1Asfo P.O. San Vito al Tagliamento, Pain Unit; 2Asfo P.O San Vito al Tagliamento Resuscitation and Intensive Therapy Unit

    2025-09-22
    https://doi.org/10.4081/ahr.2025.91
    226
  • PORTABLE PERCUTANOUS ELECTRODE NERVE STIMULATION AS A HOME-BASED THERAPY FOR TRIGEMINAL NEURALGIA, A CASE REPORT A. Bosio1, F. Baraldo2, F. Castro2, L. Carmino2 | 1Residency Program in Anesthesiology Intensive Care and Pain Management, University of Milano-Bicocca; 2Department of Anesthesiology and Pain Medicine, Cottolengo Hospital, Torino

    2025-09-22
    https://doi.org/10.4081/ahr.2025.49
    253
  • UNDERUSE OF NALDEMEDINE IN OPIOID-TREATED PATIENTS: ITALIAN REAL-WORLD EVIDENCE A. Ungar1, A. Cuomo2, F. Radaelli3, S. Calabria4, M. Leogrande4, M. Capacci5, M. Torrini6, L. Degli Esposti4 | 1Head division of Geriatrics and Intensive Care Unit, Università di Firenze, Italy; 2IRCCS Istituto Nazionale Tumori Fondazione, Napoli, Italy; 3UOC di Gastroenterologia, Ospedale Valduce, Como, Italy; 4CliCon S.r.l. Società Benefit, Bologna, Italy; 5SOD Geriatria per l'Alta Intensità e Cardiologia Geriatrica, AOU Careggi e Università degli Studi di Firenze, Italy; 6Geriatrics Unit for High Care Complexity, Università di Firenze, Italy

    2026-09-21
    https://doi.org/10.4081/ahr.2026.292
    4
  • PRELIMINARY RESULTS OF BIOWAVE® PERCUTANEOUS ELECTRICAL NERVE STIMULATION IN POST-HERPETIC NEURALGIA: DATA FROM A STRUCTURED 30-DAY PROTOCOL L. Ventura, F. Cassini, A. Berardi | University Hospital "SS. Antonio e Biagio e Cesare Arrigo", Alessandria

    2025-09-22
    https://doi.org/10.4081/ahr.2025.117
    144
  • CLINICALLY MEANINGFUL PAIN REDUCTION AND FUNCTIONAL RECOVERY AFTER PERCUTANEOUS INTRADISCAL TREATMENT FOR CERVICAL DISC HERNIATION: INTERIM RESULTS OF THE GENESIS STUDY A. Mengri1, M. Sofia2, L. Mantegazza1 | 1Pain Therapy Unit, Vimercate Hospital, ASST Brianza, Vimercate (MB), Italy; 2Medical Directorate, ASST Brianza, Vimercate (MB), Italy

    2026-09-21
    https://doi.org/10.4081/ahr.2026.264
    104
  • TRANSARTERIAL EMBOLIZATION FOR CHRONIC SHOULDER TENDINOPATHY AND BURSITIS: EARLY CLINICAL OUTCOMES USING DEGRADABLE STARCH MICROSPHERES A. Zolovkins, G. Orgera, E. Ronconi, M. Doddi, A.M. Tipaldi, M. Rossi | Interventional Radiology Unit, Sant'Andrea Hospital, Sapienza University of Rome, Italy

    Fondazione Paolo Procacci
    2026-05-06
    https://doi.org/10.4081/ahr.2026.206
    123
  • PERCUTANEOUS NUCLEOPLASTY FOR THE TREATMENT OF SYMPTOMATIC INTERVERTEBRAL DISC PROTRUSIONS USING NAVIGABLE PLASMA COBLATION DEVICE A. Zolovkins, G. Orgera, M. Doddi, S. Pulcinelli, E. Ronconi | Interventional Radiology Unit, Sant'Andrea Hospital, Sapienza University of Rome, Italy

    Fondazione Paolo Procacci
    2026-05-06
    https://doi.org/10.4081/ahr.2026.205
    245
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Advancements in Health Research

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eISSN: 3035-1103

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