https://doi.org/10.4081/ahr.2025.93
THE MOST RECENT RESEARCH SUPPORTS THE MOST ANCIENT TRADITIONS: THE EXAMPLE OF SCIATICA
L. Pella1, P. Baldini2 | 1Physiotherapist, Millesimo (SV); 2Anesthesiologist, Aosta
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Published: 22 September 2025
Before the anatomical understanding of nerves and the issues related to compression and/or physiological alterations, classifications of radiculopathies were empirical and based on the distinction between “hot” and “cold” syndromes. Some studies now demonstrate the involvement of autonomic function, echoing this traditional differentiation between hot and cold. Similarly, some therapies used in ancient times to treat these conditions may have seemed like mere superstition, but recent scientific evidence is beginning to clarify their mechanisms of action. For example, moxibustion—a technique from traditional Chinese medicine—involves burning mugwort cones on specific points of the body, producing a varying sensation of heat depending on the condition. A recent systematic review has identified therapies that activate TRPV1 ion channels—cellular channels sensitive to various stimuli, including heat—as among the few effective treatments for reducing pain in chronic low back pain and sciatica. In recent years, many studies have highlighted the important role of the body’s outer layer. In particular, the study of heat receptors (TRPV) and pressure receptors (Piezo), combined with new insights into the physiology of the superficial fascia and its connection to the autonomic nervous system, help us better understand the ancient belief that treating the body’s surface can influence deeper systems. Investigating the mechanisms behind certain techniques and understanding the rationale of traditional practices enables us to bridge different perspectives, integrate therapies, and ultimately enrich and improve the effectiveness of our treatments.
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