National Conference of the Italian Association for the Study of Pain
Vol. 3 No. s2 (2026): 49th National Conference of the Italian Association for the Study of Pain
https://doi.org/10.4081/ahr.2026.254

RECURRENT PREPATELLAR BURSITIS IN A SEVERELY OBESE CORTICOSTEROID-INTOLERANT OCTOGENARIAN: SERIAL ULTRASOUND IMPROVEMENT AFTER OXYGEN–OZONE THERAPY

G. Galasso, G. Lambiase, M.M. Fabris, D. Scarano, C. Amendola, D. Carbone | UOC Anestesia e Rianiazione DEA Nocera-Pagani-Scafati, Nocera Inferiore (SA), Italy

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Received: 21 September 2026
Published: 21 September 2026
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Introduction. Recurrent prepatellar bursitis may markedly limit mobility in older patients and can be difficult to treat when relevant comorbidities and corticosteroid intolerance coexist. We describe the short-term clinical and ultrasound course of a recurrent prepatellar bursitis treated with oxygen–ozone therapy combined with peri-bursal Arnica Heel Complex.
Methods. An 80-year-old severely obese woman (BMI >41) presented with recurrent prepatellar bursitis with abundant effusion documented on baseline ultrasound. Her medical history included chronic obstructive pulmonary disease and nocturnal CPAP for obstructive sleep apnea. Because of corticosteroid intolerance, she underwent infiltrative treatment with oxygen–ozone at a concentration of 7 μg/mL, total volume 10 mL, associated with peri-bursal Arnica Heel Arnica Complex. Clinical and ultrasound reassessment was performed 15 days after the first treatment. A second treatment session was then carried out, followed by a further clinical and ultrasound follow-up after 15 days.
Results. At first follow-up, local swelling had decreased, gait had improved, and ultrasound showed a reduction in bursal fluid collection. After the second treatment, further improvement was observed both clinically and sonographically, with better ambulation and additional reduction of the effusion.
Conclusions. In this case, oxygen–ozone therapy associated with peri-bursal Arnica Heel Complex was followed by progressive short-term clinical and ultrasound improvement in recurrent prepatellar bursitis in a frail elderly patient with severe obesity and corticosteroid intolerance. This minimally invasive approach may be considered in selected cases when steroid infiltration is poorly tolerated or not feasible. Further observations are needed to define its role more clearly.

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RECURRENT PREPATELLAR BURSITIS IN A SEVERELY OBESE CORTICOSTEROID-INTOLERANT OCTOGENARIAN: SERIAL ULTRASOUND IMPROVEMENT AFTER OXYGEN–OZONE THERAPY: G. Galasso, G. Lambiase, M.M. Fabris, D. Scarano, C. Amendola, D. Carbone | UOC Anestesia e Rianiazione DEA Nocera-Pagani-Scafati, Nocera Inferiore (SA), Italy. Adv Health Res [Internet]. 2026 Sep. 21 [cited 2026 Sep. 29];3(s2). Available from: https://www.ahr-journal.org/site/article/view/254