Editorials Open access

From symptom control to biological restoration: the expanding role of microfragmented adipose tissue in pain and regenerative medicine

Authors

Published
24 April 2026
Section
Editorials
DOI
10.4081/ahr.2026.143

References

  1. 1. Van Tran Y, Van Pham P, Narvaez Encinas M, et al. Regenerative medicine and microfragmented adipose tissue: the emerging role of lipogems® in pain management and tissue Repair. Preprints 2026, 2026040866. DOI: https://doi.org/10.20944/preprints202604.0866.v1
  2. 2. Vezzani B, Shaw I, Lesme H, Yong L, et al. Higher pericyte content and secretory activity of microfragmented human adipose tissue compared to enzymatically derived stromal vascular fraction. Stem Cells Transl Med 2018;7:876-86. DOI: https://doi.org/10.1002/sctm.18-0051
  3. 3. Moncada MAA, Tamayo MAN, Encinas MAN, et al. Immuno-inflammatory mechanisms in the chronification of pain. Pain Ther 2026;15:443-64. DOI: https://doi.org/10.1007/s40122-026-00818-x
  4. 4. Varrassi G, Farì G, Narvaez Tamayo MA, et al. Mixed pain: clinical practice recommendations. Front Med (Lausanne) 2025;12:1659490. DOI: https://doi.org/10.3389/fmed.2025.1659490
  5. 5. Hu X, Zhang Z, Zhang W, et al. Efficacy and safety of microfragmented adipose tissue combined with knee arthroscopy in the treatment of knee osteoarthritis: a systematic review. J Orthop Surg Res 2025;20:646. DOI: https://doi.org/10.1186/s13018-025-06006-5
  6. 6. Senesi L, De Francesco F, Marchesini A, et al. Efficacy of adipose-derived mesenchymal stem cells and stromal vascular fraction alone and combined to biomaterials in tendinopathy or tendon injury: systematic review of current concepts. Medicina (Kaunas) 2023;59:273. DOI: https://doi.org/10.3390/medicina59020273

Author Biography

  • Giustino Varrassi, Fondazione Paolo Procacci, Rome

    College of Medicine, Baghdad University, Baghdad, Iraq

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