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MULTIMODAL ELECTROPHYSIOLOGIC AND CEREBRAL PERFUSION ASSESSMENT OF LOSS OF CONSCIOUSNESS IN CALVES DURING SLAUGHTER: TRANSLATIONAL IMPLICATIONS FOR PAIN CONSCIOUSNESS MONITORING V.P. Pham1, V.Y. Tran2, A.A. Al Alwany3, G. Farì4, D. Myrcik5, N. Cimini6, M.L.G. Leoni7, G. Varrassi8 | 1Department of Biomedical Engineering, International University, Vietnam National University, Ho Chi Minh city, Vietnam; 2Department of Biomedical Engineering, International University, Vietnam National University, Ho Chi Minh City, Vietnam; 3College of Medicine, University of Baghdad, Iraq; 4Department of Experimental Medicine (Di.Me.S.), University of Salento, Lecce, Italy; 5Department of Internal Diseases Propaedeutics and Emergency Medicine, Medical University of Silesia, Bytom, Poland; 6Department of MESVA, University of L’Aquila, Italy; 7Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Italy; 8Fondazione Paolo Procacci, Rome, Italy
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PAIN AS A NEUROCARDIAC STRESSOR: REFRAMING PAIN BEYOND NOCICEPTION C. Angeletti1, G. Di Giuseppe1, I. Olivieri1, G. Varrassi2 | 1Department of Anaesthesia, Intensive Care and Pain Medicine, Mazzini Hospital, Teramo, Italy; 2Fondazione Paolo Procacci, Rome, Italy
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DYSPHAGIA IN OLDER ADULTS WITH ADVANCED CANCER: A PILOT CROSS-SECTIONAL STUDY N. Nowak1, D. Myrcik2, G. Varrassi3, U. Michalik-Marcinkowska4, K. Walkiewicz2, M. Muc-Wierzgoń2, M. Syrkiewicz-Świtała5 | 1Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, Bytom, Poland; 2Department of Propaedeutics of Internal Diseases and Emergency Medicine, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, Bytom, Poland; 3Fondazione Paolo Procacci, Rome, Italy; 4Department of Family Medicine and Public Health, Faculty of Medicine, University of Opole, Poland; 5Department of Health Economics and Health Management, Medical University of Silesia in Katowice, Bytom, Poland
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BEYOND ANALGESIA: FASCIAL PLANE BLOCKS AS MODULATORS OF THE SURGICAL STRESS RESPONSE C. Angeletti, I. Olivieri, G. Di Giuseppe, G. Varrassi | Department of Anesthesia, Intensive Care and Pain Medicine, Mazzini Hospital, Teramo, Italy
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SEVERE PAIN AND NEUROLOGICAL SYMPTOMS AS AN INITIAL MANIFESTATION OF PARANEOPLASTIC SYNDROME: A CASE REPORT A. Górecka1, D. Myrcik2, U. Michalik-Marcinkowska3, G. Varrassi4, K. Walkiewicz2, M. Muc-Wierzgoń2, M.S. Świtała5 | 1Department of Health Risk Management, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, Bytom, Poland; 2Department of Propaedeutics of Internal Diseases and Emergency Medicine, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, Bytom, Poland; 3Department of Family Medicine and Public Health, Faculty of Medicine, University of Opole, Poland; 4Fondazione Paolo Procacci, Rome, Italy; 5Department of Health Economics and Health Management, Medical University of Silesia in Katowice, Bytom, Poland
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ADVANCES IN THE PATHOPHYSIOLOGY AND MANAGEMENT OF CANCER PAIN: A SCOPING REVIEW Y. Tran Van1, A. Paladini2, V.P. Pham1, A.A. Al Alwany3, G. Farì4, A. Caruso5, M. Mercieri6, M.L.G. Leoni7, J.V. Pergolizzi8, A.D. Kaye9, F. Breve10, A. Corriero11, C. Gharibo12, G. Varrassi13 | 1Department of Biomedical Engineering, International University, Vietnam National University, Ho Chi Minh City, Vietnam; 2Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; 3College of Medicine, University of Baghdad, Iraq; 4Department of Experimental Medicine (Di.Me.S.), University of Salento, Lecce, Italy; 6Department of Surgery, ASST Lodi, Lodi, Italy; 7Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Italy; 8NEMA Research Inc., Naples, FL, USA; 9Department of Anesthesiology, LSU Health, Shreveport, LA, USA; 10School of Pharmacy, Temple University, Philadelphia, PA, USA; 11Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy; 12Department of Anesthesiology, NYU Grossman School of Medicine, New York, NY, USA; 13Fondazione Paolo Procacci, Rome, Italy
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DEEP BRAIN STIMULATION FOR REFRACTORY CHRONIC PAIN: CLINICAL TARGETS, INDICATIONS, AND EMERGING STRATEGIES L. Al-Husinat1, S. Azzam1, S. Al Sharie2, A.A. Alomari3, A. Baydoun4, H.B. Yaseen5, G. Varrassi6 | 1Department of General Surgery and Anesthesia, Faculty of Medicine, Yarmouk University, Irbid, Jordan; 2Laboratory of Science and Translation in Critical Illness, Vanderbilt University Medical Center, Nashville, TN, USA; 3Section of Neurosurgery, Department of Special Surgery, Faculty of Medicine, Mutah University, Alkarak, Jordan; 4Unit of Anesthesia, Intensive Care and Pain Therapy, Sant’Andrea University Hospital, Rome, Italy; 5Department of Anesthesia and Intensive care unit, Ministry of Health Educational Hospitals, Amman, Jordan; 6Fondazione Paolo Procacci, Rome, Italy
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MICROBIOTA–IMMUNE–BRAIN MECHANISMS IN CHRONIC PAIN: A STRUCTURED NARRATIVE SYNTHESIS OF TRANSLATIONAL AND CLINICAL EVIDENCE Y. Tran Van1, P.P. Van1, C.B.N. Uyen2, A. Caruso3, G. Farì4, M.L.G. Leoni5, G. Varrassi6 | 1Department of Biomedical Engineering, International University, Vietnam National University, Ho Chi Minh City, Vietnam; 2Department of Anesthesiology, Vinmec Central Park Hospital, Ho Chi Minh city, Vietnam; 3Department of Surgery, ASST Lodi, Lodi, Italy; 4Department of Experimental Medicine (Di.Me.S.), University of Salento, Lecce, Italy; 5Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Italy; 6Fondazione Paolo Procacci, Rome, Italy
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EMOTIONAL PAIN IN OLDER ADULTS: DETERMINANTS AND CLINICAL CORRELATES U. Michalik-Marcinkowska1, D. Myrcik2, G. Varrassi3 | 1Department of Family Medicine and Public Health, Faculty of Medicine, University of Opole, Poland; 2Department of Propaedeutics of Internal Diseases and Emergency Medicine, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, Poland; 3Fondazione Paolo Procacci, Rome, Italy
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SPECIFICITY OF PAIN PERCEPTION AND REPORTING IN OLDER ADULTS: A RETROSPECTIVE STUDY U. Michalik-Marcinkowska1, D. Myrcik2, G. Varrassi3 | 1Department of Family Medicine and Public Health, Faculty of Medicine, University of Opole, Poland; 2Department of Propaedeutics of Internal Diseases and Emergency Medicine, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, Poland; 3Fondazione Paolo Procacci, Rome, Italy
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FROM DYSBIOSIS TO CENTRAL SENSITIZATION: A SCOPING REVIEW OF GUT-BRAIN SIGNALING IN FIBROMYALGIA V.P. Pham1, V.Y. Tran1, F. Breve2, M.L.G. Leoni, D. Myrcik4, G. Varrassi5|6 | 1Department of Anesthesiology, Tam Anh General Hospital, Ho Chi Minh city, Vietnam; 2Mid Atlantic PharmaTech Consultants LLC; Temple University School of Pharmacy, Philadelphia, PA , USA; 3Department of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Italy; 4Department of Internal Diseases Propaedeutics and Emergency Medicine, Medical University of Silesia, Bytom, Poland; 5Department of Research, Fondazione Paolo Procacci, Rome, Italy; 6College of Medicine, University of Baghdad, Iraq
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EMERGING DRUGS OF ABUSE IN THE CHRONIC PAIN POPULATION: A CLINICAL PHARMACOLOGY PERSPECTIVE ON KRATOM, NOVEL SYNTHETIC OPIOIDS, DESIGNER BENZODIAZEPINES, GABAPENTINOIDS, XYLAZINE, AND KETAMINE F. Breve1, G. Varrassi2, J. Pergolizzi3, R. Raffa4 | 1Mid Atlantic PharmaTech Consultants LLC, Ventnor City, NJ, USA; Temple University School of Pharmacy, Philadelphia, PA, USA; 2Fondazione Paolo Procacci, Rome, Italy; 3NEMA Research Inc., Naples, FL, USA; 4Temple University School of Pharmacy, Philadelphia, PA, USA; University of Arizona College of Pharmacy, Tucson, AZ, USA
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